The model also included potential covariates such as hypertension, diabetes, eGFR, preoperative serum creatinine, preoperative BUN, ΔCopeptin, T0 aldosterone, T0 NT-proBNP, age, and sex, but these factors were not significantly associated with diuresis in the final model (p > 0.05). The gene discussed is NPPB; the disease is diabetes mellitus.