Furthermore, they used cholesterol efflux experiments and quantitative PCR to determine that iristectorigenin B enhances cholesterol efflux by inducing ATP binding cassette transporter A1(ABCA1) and ATP binding cassette subfamily G Member 1 (ABCG1), thereby demonstrating hypocholesterolemic effects without inducing hepatic steatosis [102]. Here, ABCG1 is linked to Hepatic steatosis.