Additionally, the expression of FOXP3/CD3 was significantly higher in cases with lymph node metastasis (p = 0.007), with a mean of 0.34 ± 0.26 in N0 and 0.49 ± 0.29 in N1 + 2. The gene discussed is FOXP3; the disease is metastatic malignant neoplasm in the lymph nodes.