Gene expression changes measured in tumours from compound-treated versus vehicle-treated mice showed a statistically significant upregulation of genes related to chemokines involved in lymphocyte chemotaxis (CCL4, CCL5, and CXCL10), with a significant increase in CCL4 and CCL5 of 60 mg/kg (p < 0.05) [Figure 6]. The gene discussed is CCL5; the disease is neoplasm.