Nowadays, Glucagon-Like Peptide-1 Receptor positron emission tomography (GLP-1R PET/CT) after injection of 68Ga-DOTA-exedin-4 offers a non-invasive method to detect benign insulinomas, exploiting the high expression density of GLP-1 receptors on insulinoma cells; however, this technique is not universally available [11,12]. This evidence concerns the gene GLP1R and pancreatic insulinoma.