DUXAP10 expression is significantly higher in some patients with anaplastic thyroid cancer, and we developed a cell model that describes the consequences of the anaplastic thyroid cancer proliferative and metastatic cascade when this RNA molecule is overexpressed, and how these cancer-promoting mechanisms can be alleviated by gene-specific targeting and lowering of this RNA molecule’s expression. This evidence concerns the gene DUXAP10 and thyroid gland undifferentiated (anaplastic) carcinoma.