In the multivariable OS cox analysis (Results S5), ALP level increase (HR: 1.93, 95% CI: 1.18–3.17; p = 0.009), decreased albumin levels (HR: 1.92, 95% CI: 1.18–3.13; p = 0.008), and the development of hyponatremia (HR: 1.79, 95% CI: 1.05–3.04; p = 0.033) remained independent prognostic factors for worse survival. The gene discussed is ALB; the disease is Hyponatremia.