For TLR-4, the rs4986790 (NcoI) polymorphism, which causes an amino acid exchange from aspartate to glycine (AA/AG), showed that individuals with the homozygous AA genotype had a significantly higher risk of cervical dysplasia than those with the AG genotype, with odds ratios suggesting a threefold increase in risk. Here, TLR4 is linked to cervical intraepithelial neoplasia.