In pancreatic tumors, the most common fusion genes are B-Raf (BRAF), Fibroblast Growth Factor Receptor 2 (FGFR2), Rearranged During Transfection (RET), and anaplastic lymphoma kinase (ALK); however, the ALK, FGFR2, Neuregulin 1 (NRG1), neurotrophic receptor tyrosine kinase (NTRK), Mitogen-Activated Protein Kinase (MET), and RET fusions were seen typically in PDAC [22]. The gene discussed is ALK; the disease is pancreatic neoplasm.