CD274 and Miyoshi myopathy: A study by Ray et al. also showed that an inhibition of the PD1-PD-L1 axis did not affect the ability of pDCs to induce MM proliferation and survival; however, they did report that PD-L1 inhibition resulted in pDC-MM cell interactions that up-regulate PDL1 expression in both cell types and generate MM-specific cytotoxic T cells capable of eliminating previously drug-resistant MM cells [8].