RBM20 and familial dilated cardiomyopathy: This is due to the genes involved often being common, as demonstrated by the desmosomal mutations (PKP2, DSP, DSG2, and DSC2) caused by genes typically associated with ARVC genes [25], FLNC truncating variants that lead to DCM with arrhythmogenic features [31], and RBM20 (p.Arg636Cys), MYH7, SCN5A, PKP2, and mutations predisposing individuals to arrhythmic risk and sudden cardiac death [35,36].