When the predictive power of parameters included and excluded from the ISTH score was evaluated using multivariate regression analysis in patients diagnosed with AML-M3 and DIC (Table 3), prothrombin time, D-dimer, platelet count, LDH, hemoglobin, and INR were not significant predictors (p > 0.05). The gene discussed is F2; the disease is acute myeloid leukemia.