Alternatively, assessing other targets like NF-κB, other metrics of pro- and anti-inflammatory activity [70,71], brain levels of inflammatory biomarkers such as TSPO, inflammatory markers in CSF, or stimulated cytokine expression, may help to determine if the immune effects of blueberries play a role in their therapeutic effects in MDD and GAD. Here, NFKB1 is linked to major depressive disorder.