These terms included, body weight, overweight, obesity, satiety, cholecystokinin, insulin, glucose, diabetes, metabolic, cardiometabolic, lipids, cholesterol, triglycerides, high density lipoprotein (HDL), low density lipoprotein (LDL), vascular, flow-mediated dilation (FMD), blood flow, endothelial function, heart, blood pressure, brain, cognition, Alzheimer’s disease, neurocognition, neuroscience, longevity, gut, microbiome, and related terms. The gene discussed is INS; the disease is obesity due to melanocortin 4 receptor deficiency.