Gao et al. reported that L. rhamnosus EPS alleviates S. typhimurium-induced intestinal inflammation in mice, reducing the levels of pro-inflammatory (TNF-α and IL-1β) and increasing the levels of the anti-inflammatory cytokine IL-10, thereby contributing to immune homeostasis and exerting protective effects in intestinal disease models [65]. This evidence concerns the gene TNF and intestinal disorder.