Our screening in the DisGeNET biomedical database showed results such as ataxia, a disease with a clear link to the CaMBD mutation in the PMCA3 isoforms (ATP2B3 gene) reported in the literature [6,25,26], which highlights the importance of this region, even more considering the high expression of this isoform in the nervous system. Here, ATP2B3 is linked to Ataxia.