As shown in Figure 5A,B, to explore how SOX18 and SOX30 are epigenetically regulated in non-small-cell lung cancer (NSCLC), we analyzed the methylation status of three distinct CpG islets within their promoter regions across 30 patient samples (LSCC, n = 15; LUAD, n = 15). Here, SOX18 is linked to non-small cell lung carcinoma.