TNNI3 and skeletal muscle disorder: Although there are biochemical differences among them, in clinical practice, there are no significant differences, and detection of both hs-cTnI and hs-cTnT is used equally in everyday clinical practice, except in specific (and already known) clinical conditions such as skeletal muscle disorders/diseases (in which the hs-cTnI level should be determined to check if the heart is also involved) [4].