BNP or NT-proBNP levels ranged from normal to significantly increased, suggesting cardiac stress or heart failure [13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42]. The gene discussed is NPPB; the disease is heart failure.