Qidan Tangshen Granule may provide clinical benefits by reducing oxidative stress, improving blood glucose levels, and enhancing renal function, demonstrating potential as an adjunctive therapy; short-term curcumin supplementation can reduce proteinuria and inflammatory factors (TGF-β, IL-8) in patients with overt T2DM-related DKD. This evidence concerns the gene TGFB1 and diabetic kidney disease.