We have obtained in silico data on the serious functionality of the endometriosis-causal SNP rs440837 (A > G) ZBTB10 and 5 proxy loci: they were localized in sites of potential promoters/enhancers, active promoters/enhancers in the DNA region of three genes such as RP11-48B3.3, RP11-48B3.4, ZBTB10, and affect this genome region interaction with 22 TFs. The gene discussed is ZBTB10; the disease is endometriosis.