Interestingly, previously we showed an association with breast cancer risk in 8 out of 9 SNPs and the identical loci panel in the same population [78], what may indicate the “universal” role of GWAS-important genetic determinants of SHBG in the development of female reproductive sphere hormone-dependent diseases (endometriosis, breast cancer) in the population of Europeans in Russia. Here, SHBG is linked to breast cancer.