SP1 and neoplasm: It is indicated that ZBTB10 inhibits the production of vascular endothelial growth factor (VEGF), its receptors of the first and second types (VEGFR1/VEGFR2), and survivin, and decreases mRNA/protein expression of specificity protein (Sp) TFs such as Sp1, Sp3, Sp4, which are responsible for the processes of tumor angiogenesis/growth/metastasis [75,76], and these biological pathways are also important for the biology of endometriosis [79].