Secondly, in the work of Garitazelaia et al., in which MR analysis did not demonstrate statistically significant causal relationships between the GWAS-impact determinant of the sex hormone levels and endometriosis, pleiotropic genetic associations of two loci (rs11031002; rs11031005) of the FSHB gene with endometriosis and sex hormone contents were registered (and this, as the authors themselves note, came as a surprise to them)! Here, FSHB is linked to endometriosis.