The works of these scientists indicate a pronounced effect on the hypothalamic-pituitary-gonadal system of the female fetus (in the prenatal period of its development) of low testosterone levels, which leads to its “reprogramming” and the formation of a certain endometriosis-predisposing pattern of the hormonal profile of these fetuses (reduced LH compared with FSH, increased SHBG, reduced systemic/ovarian testosterone, etc.)[40,41,42]. This evidence concerns the gene SHBG and endometriosis.