Paired antagonistic interactions with a contribution to trait entropy (endometriosis risk) from −0.15% to −0.23% were recorded when visualizing and evaluating the strength of the influence of the most significant endometriosis-associated five-locus SNP-SNPinter model, rs8023580 NR2F2-rs7910927 JMJD1C-rs440837 ZBTB10-rs3779195 BAIAP2L1-rs780093 GCKR (Figure 1). The gene discussed is JMJD1C; the disease is endometriosis.