Macrophages and T lymphocytes are activated in response to the presence of tumours and, by releasing cytokines such as TNF-α, IL-6 and interferon-γ (IFN-γ), promote an inflammatory response that not only intensifies local inflammation at different sites, but is also involved in protein catabolism, leading to the loss of both fat and muscle tissue [26,27]. The gene discussed is IL6; the disease is neoplasm.