Constitutive NF-κB signaling maintains continuous expression of anti-apoptotic genes, including Bcl-2, B-cell lymphoma-extra large (Bcl-xL), and members of the inhibitor of apoptosis (cIAP) family, providing ovarian cancer cells strong resistance to apoptosis and contributing to poor responses to platinum drugs and taxanes [12]. This evidence concerns the gene NFKB1 and ovarian cancer.