GPT and steatosis: We showed that, unlike the minimal liver injury and absence of inflammation observed after acute EtOH exposure, CBE treatment produced a marked increase in serum ALT (~350 U/L) that was accompanied by micro- and macrovesicular steatosis, necrosis, apoptosis, inflammasome activation, proinflammatory cytokine production, and leukocyte infiltration (Figure 2 and Figure 3).