CHI3L1 and colorectal carcinoma: There is also a work by De Robertis et al. [36] where the authors, using cell lines, also confirmed that high-YKL-40-expressing cells showed increased motility, invasion, and proliferation, and additionally tested serum samples from CRC patients had elevated YKL-40 levels, which simultaneously correlated with high-grade tumors, which clearly confirms previous reports and our findings.