In addition, five programs were present only in subsets of cancer types, including metabolism (Program 6: ACER2, ALDOB, etc.), epithelial differentiation (Program 7: KRT5, S100A7, etc.), oxidative phosphorylation (Program 8: ATP5F1B, COX4I1, etc.), protein synthesis (Program 9: HSPA5, HSPA8, etc.), and RNA processing (Program 10: CCNL1, DDX17, etc.). This evidence concerns the gene COX4I1 and cancer.