A significant increase in mRNA expression levels was observed in tumor tissue compared with normal tissue for the following genes: TAGLN2 (2-fold, p < 0.0001), ENO1 (1.49-fold, p < 0.0001), GLRX2 (1.73-fold, p < 0.0001), PLOD1 (1.72-fold, p < 0.0001), PRDX4 (1.81-fold, p < 0.0001), and TMED9 (2.28-fold, p < 0.0001) (Figure 6B). The gene discussed is ENO1; the disease is neoplasm.