EGFR and non-small cell lung carcinoma: Furthermore, knockdown of SULF1 suppressed key malignant behaviors in NSCLC cell lines, including NCI-H1299 (CRL-5803) and HCC827 (CRL-2868), by reducing cell proliferation, migration, invasion, and epithelial–mesenchymal transition (EMT) through inhibition of the EGFR/MAPK signaling pathway [26].