↓ LVEDD, LVESD, LVESV, LVEDV↑ EF, FS↓ hypertrophy, HW/BW, LVW/BW, LVW/TL↓ fibrosis↓ CK-MB, cTn-I, NT-proBNP, p-cTn-I↓ apoptosis, Bax↓ Bcl-2. The gene discussed is NPPB; the disease is hypertrophy.