Although multiple granzyme genes in CD8+ TIL were increased with IL-15 complexes and anti-PD-1 treatment and correlated with the overall influx of CD8+ T cells (Figure 3B, C) within the tumor parenchyma, the gene expression of granzyme B was not increased as determined using Nanostring® (Figure 3D). Here, GZMB is linked to neoplasm.