Qi et al. (2021) examined the role of BRINP3 and CXCR2 gene polymorphisms and observed that the CT genotype of CXCR2 rs2230054 and the AG genotype of rs1126580 were more frequent in IP patients, suggesting a role for CXCR2 in the development of the disease [19]. The gene discussed is BRINP3; the disease is incontinentia pigmenti.