For example, after virus infection, pattern recognition receptors (PRRs) such as Toll-like receptors (TLRs), cytoplasmic NOD-like receptors (NLRs), intracellular retinoic acid-inducible gene-I-like receptors (RLRs), and cyclic GMP-AMP synthase (cGAS) in host cells recognize the dsRNA or DNA of the viruses, and the antiviral natural immune response pathway is activated to resist virus invasion [1,2,3,4,5]. The gene discussed is CGAS; the disease is viral infectious disease.