In experiments where melanoma cells were injected into mice and treated with diallyl trisulfide (DATS), the results showed: (1) inhibited growth of melanoma; (2) reduced immunosuppressive activity of myeloid-derived suppressor cells (MDSCs) in the spleen, blood, and tumor microenvironment; and (3) restored function of CD8 T cells and dendritic cells. This evidence concerns the gene CD8A and neoplasm.