Preliminary screening of cytotoxic activity in leukemia and lymphoma cells demonstrated the highest affinity in silico for the most cytotoxic compound, 1-[4-(benzyloxy)phenyl]-2-(hexylamino)ethanol (10S-E2), as well as less toxic synephrine derivatives with the potential to bind GR: 2-(hexylamino)-1-(4-methoxyphenyl)ethanol (4S-C2), 1-(4-(benzyloxy)phenyl)-2-((2-hydroxyethyl)amino)ethanol (8S-E3) and 2-(hexylamino)-1-(4-nitrophenyl)ethanol (13S-G2) (Figure 1 and [32]). This evidence concerns the gene NR3C1 and lymphoma.