Analysis of the top 10 differentially expressed genes compared with the control group, Cxcl9, Caspase12, which are genes associated with IBD, increased with DSS treatment but decreased after the L. rhamnosus MS27 addition, but Cxcl1 increased with the L. rhamnosus MS27 treatment (Figure 4B). The gene discussed is CXCL1; the disease is inflammatory bowel disease.