Those with ductal cancer in situ, those whose tumour cells express the oestrogen receptor (ER) and the progesterone receptor (PgR) with a low proliferation rate as determined by the expression of Ki67 (<14%), known as Luminal A; Luminal B which expresses the ER but not the PgR and has a Ki67 (>14%). This evidence concerns the gene PGR and neoplasm.