CTNNB1 and colorectal carcinoma: Conversely, Escobar et al. observed a higher incidence of FBXW7 mutations in older CRC patients compared with those harboring CTNNB1 mutations (median age 61.1 vs. 52.4 years, p = 0.037) (median age of 52.4 vs. 61.1, p = 0.037) [74].