Within this term, critical genes include neural cadherin (cdh2), a calcium-dependent cell adhesion molecule essential for neural cell–cell adhesion that is robustly associated with neurodevelopment and neurodegenerative diseases [67]; voltage-gated and ligand-gated potassium channels (kcnc1a and kcnma1a), which are vital for proper voltage conductance in neuronal cells [96,97]; and GRIN family members (grin1a and grin2ca), which are required for neurotransmission [68]. Here, CDH2 is linked to neurodegenerative disease.