ABCA1 and neoplasm: ABCA1 is strongly expressed in both malignant cholangiocytes (log2FC: 23.16; padj = 1.35 × 10−117) and tumor-associated macrophages (log2FC: 4.09; padj = 2.45 × 10−279), suggesting dysregulated cholesterol efflux in both epithelial and immune compartments.