Another report by Ren et al. demonstrated a positive correlation between NHR and biochemical indicators of myocardial ischemia, such as cTnI (cardiac-specific troponin I), CK-MB (creatine kinase–myocardial band), and LDH (lactate dehydrogenase), in patients with acute coronary syndrome and T2DM. Here, TNNI3 is linked to type 2 diabetes mellitus.