To explore the potential interaction between the frequencies of cytotoxic T cell subsets and the various T cell differentiation subsets, especially the senescent CD57+CD28- subsets, we next performed correlation analyses between the frequencies of different cell populations on all the samples (n = 335) or by the two clinical groups separately (n = 132 for ME-MM, n = 203 for ME-SA). Here, CD28 is linked to Miyoshi myopathy.