To determine the functional capacity of lymphocytes in people with ME-MM or ME-SA, we measured intracellular cytotoxic molecules (granzyme B and perforin) and cytokines (Interferon-γ (IFN-γ) and interleukin-17 (IL-17)) in T cells and NK cells. The gene discussed is GZMB; the disease is Miyoshi myopathy.