METTL3 and neoplasm: The TCA cycle can be indirectly regulated by RNA modifications through NSUN2 and ALKBH5, while the ETC can be mediated by METTL3, METTL8, WTAP, NSUN2, NSUN3, IGF2BP1, IGF2BP3 and ALKBH3, suggesting that RNA modifications may regulate antitumor immunity via the TCA cycle and OXPHOS in tumor cells.