METTL14 and atherosclerosis: Moreover, Yang Q et al. demonstrated that lncRNA nuclear paraspeckle assembly transcript 1 (NEAT1) is positively regulated by METTL14 and YTHDC1, which further advances the transcriptional activation of NLRP3 through its interaction with Kruppel-like factor 4 (KLF4), resulting in ameliorated atherosclerosis [33].