Conversely, another two studies conducted by Wang Y et al. and Zhu H et al. revealed that ALKBH5 enhances the stability of BCL-2 mRNA, thereby suppressing apoptosis in epithelial ovarian cancer, while the overexpression of WTAP can lead to the downregulation of BCL-2 in an m6A-dependent manner in breast cancer [244, 245]. This evidence concerns the gene ALKBH5 and ovarian carcinoma.