For instance, it was reported that triazole-based compound derivatives and triazole hybrids efficiently reduce VEGFR2 expression in MCF-7 breast cancer cells by obstructing angiogenesis and inhibiting tumor growth48 while triazole hybrids exhibit superior cytotoxicity against MCF-7 breast cancer cells compared to cisplatin, a widely utilized chemotherapeutic agent. Here, KDR is linked to breast carcinoma.