Compared with those cocultured with FLT3-ITD- blasts, HS5 cells cocultured with FLT3-ITD+ AML blasts presented higher transcript levels of CSF2 (GM-CSF), CCL2 (MCP-1), and IL6 (supplementary Fig. 5a–c). This evidence concerns the gene FLT3 and acute myeloid leukemia.