ITGAM and neoplasm: The analysis of the myeloid compartment revealed an increase in the proportion of CD11b+Gr-1+Ly6G+Ly6Clow cells—in tumor-bearing mice, defined as polymorphonuclear (PMN)-MDSCs as previously described39—that were found in the PB and spleens of OSM-overexpressing mice but not in those of WT mice (Fig. 3k, l).