Compared with those cocultured with FLT3-ITD- blasts, HS5 cells cocultured with FLT3-ITD+ AML blasts presented higher transcript levels of CSF2 (GM-CSF), CCL2 (MCP-1), and IL6 (supplementary Fig. 5a–c). The gene discussed is CSF2; the disease is acute myeloid leukemia.