ATRN and obesity due to melanocortin 4 receptor deficiency: Obesity is recognizedfor its association with a chronic low-grade inflammatory state andimmune system dysfunction. There is alarge volume of accumulated evidence that weight loss following BSleads to adaptations of immune cell populations and allows improvementsin inflammatory markers., In our analysis, wefound that the relative abundance of proteins such as dipeptidase1, attractin, and peptidoglycan recognition protein 1 had increased2 years postsurgery.