Nine months after the first RFA procedure, the patient's serum calcitonin level had decreased significantly to less than 2 pg/mL, and the sizes of the thyroid tumor were 7.7 × 9 × 13.6 mm (0.49 mL), and the tumor was stable biochemically and structurally over 6 months after the second ablation (Figure 2). The gene discussed is CALCA; the disease is neoplasm.