Lakkadwala S et al. (Lakkadwala and Singh, 2019) demonstrated that liposomes surface-modified with transferrin (Tf) for receptor targeting and with cell-penetrating peptide PFVYLI (PFV) increased the translocation of doxorubicin (Dox) and erlotinib (Erlo) across the BBB into glioblastoma (U87) tumor cells. The gene discussed is TF; the disease is glioblastoma.