Compared with the control group, curcumin significantly reduced alanine aminotransferase (ALT), aspartate aminotransferase (AST), total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL) (alleviated dyslipidemia), NAFLD Activity Score (NAS), body weight, liver weight, liver index and inflammatory cytokines (tumor necrosis factor-α (TNF-α), interleukin-1 (IL-1), and interleukin-6 (IL-6)). Here, IL6 is linked to metabolic dysfunction-associated steatotic liver disease.