ROC analysis demonstrated exceptional diagnostic accuracy for CAD detection: IFITM1 (AUC 0.9375, sensitivity 95%, specificity 81.25%), IFITM2 (AUC 0.8984, sensitivity 90%, specificity 75%), and IFITM3 (AUC 1.000, sensitivity 97.5%, specificity 100%). The gene discussed is IFITM3; the disease is coronary artery disorder.