BRCA1/2, a known mutation in breast cancer, was identified in iPanels of 9 patients and is known to be associated with genes involved in the TGF-\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{upgreek}\usepackage{mathrsfs}\setlength{\oddsidemargin}{-69pt}\begin{document}$\beta$\end{document} pathway, eventually leading to a disrupted cell cycle regulation. The gene discussed is BRCA1; the disease is breast carcinoma.