ACE and coronary artery disorder: In the final adjusted model for age, sex, ethnicity, BMI, SBP, HbA1c, lipid profiles, baseline eGFR, pre-existing CAD or PVD, use of angiotensin converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) and statin, the highest NLR was associated with a 1.63-fold increased risk for all-cause mortality (HR 1.63; 95% 1.18 – 2.27, p=0.003) (Table 2b).